I stayed on plavix for 6 months (along with low-dose aspirin which I continue to take) and couldn't stand the side effect of severe bruising. My recovery was slow in that I continued to experience lots of chest pain with stress, and was eventually diagnosed with GERD, which I believe was caused either by the stents or the plavix. Bruising (ecchymosis) happens when small blood vessels (capillaries) under the skin break. This causes bleeding within skin tissues. You will also see discolorations from the bleeding. It seems almost automatic that someone on Plavix/aspirin (after Drug coated stent), will be at risk for bruising. My questions have to do with severity and trends (getting worse over time, for example). I have been on Plavix for alittle over 5 years now and have always noticed I bruise very easy. Recently however it seems the bruising has really gotten bad. Edta plavix He died in january, the month when english roads edta plavix were at their most impassable. Frank caught sturms wrist with both hands, but sturm snaked his left arm around franks neck, squeezing at the carotid artery, trying to get frank to black out as he clung like one of the spider monkeys. My husband takes plavix as well as lasinapril, aspirin, etc and i can say YES he dose bruise very easy. Unfortunately I do not know which of these meds cause the bruising. Plavix (clopidogrel) prevents platelets in your blood from sticking together to form an unwanted blood clot that could block an artery. Plavix is used to lower your risk of having a stroke, blood clot, or serious heart problem after you've had a heart attack, severe chest pain , or circulation problems. Doctors give unbiased, trusted information on whether Plavix can cause or treat Bruising: Dr. Grin on what to do about plavix bruising: If acute-- get it drained-- easy procedure. I've been on it almost 2 weeks and have noticed that I'm bruising more easily. I've got various little bruises. I think they are from little knocks, but the sort of thing you do every day and not bruise from if you see what I mean. Since taking Plavix and aspirin I have severe bruising. I try to be careful but bruise just brushing against a doorway, for example. My dog was sitting on my lap and when he jumped off to the floor the pressure of lifting off caused bruising on both legs.